We
offer a Complete Range of Diagnostic and Treatment Services
Expert care is available for patients experiencing any degree of IBD,
from mild cases requiring only minor medication changes and lifestyle
adaptations, to extreme cases demanding technically sophisticated
intervention.
Each
patient is evaluated and a personalized treatment plan is developed.
Review of previous endoscopies, radiologic studies, and pathology
is provided by gastroenterologists whose sole focus is IBD.
Diagnosis
Because effective management of an IBD patient hinges on pinpointing
the exact type, extent, and severity of the disease, our Center offers
a range of highly sophisticated diagnostic options, including wireless
capsule endoscopy pioneered by Mount Sinai gastroenterologists. Novel
radiologic imaging approaches such as CT enterography and MR enterography
are also available, allowing examination of complications in exceptional
anatomic detail.
When non-invasive testing is inconclusive, laparoscopy performed by
world leaders in this technique can be used safely to diagnose the
most difficult cases.
Treatment
At Mount Sinais Center for Inflammatory Bowel Disease, patients
benefit from individualized treatment plans that combine the latest
medical or surgical therapies with established approaches.
Medication
Our inpatient service is expert at caring for patients requiring intravenous
cyclosporine therapy. At our infusion center, specially-developed
protocols permit the safe administration of infliximab (Remicade®),
even to patients with prior infusion reactions. Other infusion-based
therapies such as human intravenous gammaglobulin, leukocytapharesis,
and intravenous iron are also administered.
Surgery
Bowel-sparing surgery has been performed at Mount Sinai on thousands
of patients with Crohns disease. For patients with ulcerative
colitis failing medical therapy or with dysplasia, restorative proctocolectomies
can be performed in one or two stages by highly experienced surgeons,
frequently using minimally invasive approaches. Our colorectal surgeons
can also provide relief for patients with perianal complications of
Crohns disease.
For patients
who have endured the unfortunate consequences of extensive surgery
for Crohn's disease, Mount Sinai's Intestinal Failure and Transplantation
Program offers intestinal rehabilitation and transplantation.
Cutting
Edge Research: Clinical Trials
Clinical trials conducted at Mount Sinai have changed the face of
therapy for inflammatory bowel disease. These include 6-mercaptopurine,
cyclosporine, and, most recently, infliximab and anti-interleukin-12
antibody for active Crohns disease. Consistent with the programs
strong research focus on the genetic, immunologic, and microbiologic
aspects of IBD, Mount Sinai regularly conducts clinical trials in
the areas of biologic therapy, leukocytapharesis and other types of
immunomodulatory therapy for patients with severe or treatment-resistant
forms of IBD.
For
a current list of Clinical Trials now open to patients at Mount Sinai,
please
click here.
Basic
Science Research
Many of the clinicians caring for patients at the Center for Inflammatory
Bowel Disease are at the forefront of immunologic research that will
ultimately lead to improved IBD therapies. Our unique bench-to-bedside
approach gives patients early access to the fruits of their discoveries.
In particular,
the research at Mount Sinai focuses on the immunologic response to
bacteria in the gut, the development of tolerance to luminal antigens,
the molecular pathways leading to cancer development in IBD, and the
genetics of the disease. Our research is supported by the National
Institutes of Health and the Crohns and Colitis Foundation of
America.
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