Answer 1:
Of course ABC's. Also obtain an EKG as this is an unknown overdose in a depressed patient. A wide QRS complex may indicate or alert you to the possibility of a TCA overdose. Monitor and Pulse Ox the patient. Expose (the patient) and perform a thorough physical exam.

You should also send the roomate home to search the apartment for any bottles, and have him call you or bring them back - even the half empty ones.

done