Pharmacology and Systems Biology Multidisciplinary Training Area
OverviewThe research programs within the Pharmacology and Systems Biology (PSB) multidisciplinary training area share the following common theme. Knowledge of the health or disease state of a cell, tissue, or organism, requires an understanding of networks of molecular interactions within and between cells. Thus, new and more effective therapies can be developed by considering how biological components interact with each other to produce emergent behaviors. Accordingly the PSB curriculum emphasizes training in several disciplines and approaches ranging from molecular and cell biology to genetics and biochemistry, from physiology and pharmacology to neuroscience and computational biology, from single cell model systems to organ-level and animal studies. The PSB faculty investigate disease processes and drug actions in a variety of cell types but share the underlying philosophy that systems approaches are required for transformative advances. Because mathematics provides a common language for understanding physical and biological processes, quantitative reasoning and computational approaches are integrated into the PSB curriculum and employed by many of the PSB faculty. The core courses, journal clubs, lab rotations, and works-in-progress presentations provide our students with an understanding of how to use diverse data sets to delineate biological networks, how to translate this information into new therapeutic and preventive strategies, and how to apply this paradigm to their own research. Please direct your inquires to: |