General Information

IACUC Applications

One of the main mandates of the Institutional Animal Care and Use Committee (IACUC) is to ensure that all vertebrate animal studies are conducted in accordance with Animal Welfare Act regulations and Public Health Service policies, and that such studies conform to the Institution's Assurance1 document filed with the Office of Laboratory Animal Welfare of the NIH. To fulfill this requirement, all studies involving vertebrate animals, including pilot studies and intramural projects, must be reviewed and approved by the IACUC. Principal Investigators (PIs) are required to complete and submit an IACUC application entitled Vertebrate Animal Study. If the study involves biohazards, major surgery, genetically altered animals or production of antibodies, PIs are also required to complete additional appendices.

• Appendix A: Genetically Modified Animals is required for the production and/or use of genetically modified animals.
• Appendix B: Surgery is required if major surgery (survival or non-survival) is proposed, regardless of species.
• Appendix C: Antibody Production is required for the production of monoclonal or polyclonal antibodies.
• Biological Risk Assessment forms are required if the project involves the use of hazardous materials in vivo.

Electronic Submission of IACUC Applications

IACUC forms and appendices are available on-line via the InfoEd portal at https://eresearch.mssm.edu/.

For additional information please contact the IACUC office at (212) 241-8955.

IACUC Office Location

Annenberg Building, 26th Floor, Room 26-10, walk through security doors and make a right.

Full Committee Meetings

IACUC meetings of are held on Wednesdays every three weeks throughout the year.

Review Process

After reviewing the Vertebrate Animal Study and applicable appendices, the IACUC may approve, withhold approval, or require modifications of any proposed activities related to animal use and care. Once a study is approved, a formal letter of approval is sent by the IACUC to the investigator for use with extramural grant applications.

Studies can be initiated only after the application has been reviewed and has received a formal IACUC approval. Approvals are granted for a period of three years. For the second and third year of the approval period, only a Progress Report is required at the beginning of each project year. At the expiration of the three-year approval period, a new set of IACUC forms must be submitted.

Contact Information

For help and additional information please contact the IACUC office at (212) 241-8955 or e-mail the IACUC Administrator:
Ms. Janice Gates, M.B.A., Notary
E-mail: janice.gates@mssm.edu

Biological Risk Assessment

The Biological Risk Assessment forms are available on-line via the InfoEd portal at https://eresearch.mssm.edu/.

For additional information, please contact the Biosafety Officer:
Philip Hauck, M.S., M.S.H.S., C.B.S.P., S.M. (N.R.M.)
Tel: (212) 241-5169
E-mail: philip.hauck@mssm.edu

IACUC Office

Mount Sinai School of Medicine
One Gustave L. Levy Place
Box 1155
New York, NY 10029
Tel: (212) 241-8955
Fax: (212) 241-5550

Footnotes

1. In the Animal Welfare Assurance document (Assurance), the Institution provides an assurance that it will comply with the Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals. The Assurance is filed with the Office of Laboratory Animal Welfare (OLAW) of the NIH. The PHS guidelines on Assurance documents can be accessed at grants.nih.gov/grants/olaw/sampledoc/assursmp.htm.