Christopher F. Basler Lab Mount Sinai
New York

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Selected Publications

Park MS, Garcia-Sastre A, Cros JF, Basler CF, Palese P. Newcastle disease virus V protein is a determinant of host range restriction.J Virol. 2003 Sep;77(17):9522-32.

Flandorfer A, Garcia-Sastre A, Basler CF, Palese P. Chimeric influenza A viruses with a functional influenza B virus neuraminidase or hemagglutinin. J Virol. 2003 Sep;77(17):9116-23.

Basler CF, Mikulasova A, Martinez-Sobrido L, Paragas J, Muhlberger E, Bray M, Klenk HD, Palese P, Garcia-Sastre A. The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. J Virol. 2003 Jul;77(14):7945-56.

Park MS, Shaw ML, Munoz-Jordan J, Cros JF, Nakaya T, Bouvier N, Palese P, Garcia-Sastre A, Basler CF. Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins. J Virol. 2003 Jan;77(2):1501-11.

Basler CF, Garcia-Sastre A. Viruses and the type I interferon antiviral system: induction and evasion. Int Rev Immunol. 2002 Jul-Oct;21(4-5):305-37.

Wang X, Basler CF, Williams BR, Silverman RH, Palese P, Garcia-Sastre A. Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains. J Virol. 2002 Dec;76(24):12951-62.

Tumpey, TM, Garcia-Sastre, A, Mikulasova, A, Taubenberger, JK, Swayne, DE, Palese, P, Basler, C. Existing antivirals are affective against influenza viruses with genes from the 1918 pandemic virus.Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13849-54.

Palese P, Basler CF, Garcia-Sastre A. The makings of a killer.Nat Med. 2002 Sep;8(9):927-8.

Geiss, GK, Salvatore, M, Tumpey, TM, Carter, VS, Wang, X, Basler, C, Taubenberger, JK, Bumgarner, RE, Palese, P, Katze, MG, Garcia-Sastre, A. Cellular Transcriptional Profiling in Influenza A Virus Infected Lung Epithelial Cells: The Role of the Nonstructural NS1 Protein in the Evasion of the Host Innate Defense and Its Potential Contribution to Pandemic Influenza. Proc Natl Acad Sci U.S.A. 2002;Aug 6;99(16):10736-10741.

Salvatore M, Basler CF, Parisien JP, Horvath CM, Bourmakina S, Zheng H, Muster T, Palese P, Garcia-Sastre A. Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis. J Virol. 2002 Feb;76(3):1206-12.

Basler, CF, Reid, AH, Dybing, JK, Janczewski, TA, Fanning, TG, Zheng, H, Salvatore, M, Perdue, ML, Swayne, DE, Garcia-Sastre, A, Palese, P, Taubenberger, JK. Sequence of the 1918 pandemic influenza virus non-structural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes. Proc Natl Acad Sci U S A 2001;98:2746-2751.

Momose F, Basler CF, O'Neill RE, Iwamatsu A, Palese P, Nagata K. Cellular splicing factor RAF-2p48/NPI-5/BAT1/UAP56 interacts with the influenza virus nucleoprotein and enhances viral RNA synthesis. J Virol. 2001 Feb;75(4):1899-908.

Basler, CF, Wang, X, Muhlberger, E, Volchkov, V, Paragas, J, Klenk, HD, Garcia-Sastre, A, Palese, P. The Ebola virus VP35 protein functions as a type I IFN antagonist. Proc Natl Acad Sci U S A 2000;97:12289-12294.

Talon J, Horvath CM, Polley R, Basler CF, Muster T, Palese P, Garcia-Sastre A. Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. J Virol. 2000 Sep;74(17):7989-96.

Basler CF, Garcia-Sastre A, Palese P. Mutation of neuraminidase cysteine residues yields temperature-sensitive influenza viruses.J Virol. 1999 Oct;73(10):8095-103.

Basler CF, Droguett G, Horwitz MS. Sequence of the immunoregulatory early region 3 and flanking sequences of adenovirus type 35. Gene. 1996 May 8;170(2):249-54.

Basler CF, Horwitz MS. Subgroup B adenovirus type 35 early region 3 mRNAs differ from those of the subgroup C adenoviruses. Virology. 1996 Jan 15;215(2):165-77.

This page was made by Mark Chua
Last Updated August 29, 2003