Construction, Analysis and Visualization of a Large-scale Signaling Network in Hippocampal Neuronal Mammalian Cells

Index of Nodes

Name Type Location Links In Links Out Links CC Avg. Path Length
A1RReceptorMembrane31204.27512
A2ARReceptorMembrane31204.27677
AALipidCytosol21113.73311
ABLKinaseCytosol10350.08888893.36079
AC1CyclaseCytosol54103.62932
AC2CyclaseCytosol54103.5173
AC5CyclaseMembrane7610.0476193.44152
ACHLigandExtracellular40405.1911
ACTINCytoskeletonCytosol19600.02339183.49094
ADAPTINAdapterCytosol40303.89621
ADDUCINAdapterCytosol33003.42998
ADENOSINELigandExtracellular20205.26689
ADPRIBSYCYCLASESynthaseCytosol21104.67875
AKAPAdapterCytosol5100.13.28336
AKAP15AdapterCytosol20013.68863
ALPHA1ARReceptorMembrane41304.27018
ALPHA2ARReceptorMembrane41304.27183
ALPHA7NACHRReceptorMembrane21104.89456
ALPHAACTININCytoskeletonCytosol11300.1272733.34926
ALPHACATENINCytoskeletonCytosol10004.62438
AMISYNVesicleVesicles20214.26524
AMPARChannelMembrane15710.02857143.22735
AMPHIPHYSINAdapterCytosol10004.15321
ANANDAMIDELigandExtracellular20205.26359
ANKYRINCytoskeletonCytosol61003.8056
ANPLigandExtracellular10106.03789
AP2AdapterVesicles7000.09523813.83526
APAF1AdapterCytosol43104.56837
APCAdapterCytosol31114.07249
APOLLONUbiquitinaseCytosol20204.76606
APSAdapterCytosol3110.3333334.13674
ARFGTPaseVesicles64104.27842
ARFGAPGAPVesicles10105.27677
ARFGEFGEFVesicles10105.27677
ARH2GEFCytosol30203.99012
ARIP2AdapterCytosol10005.52389
ARNOGEFCytosol32103.98517
ARP23CytoskeletonCytosol3210.3333334.14662
ASK1KinaseCytosol31203.98682
ATF1TFNucleus4400.53.67545
ATF2TFNucleus6330.1333334.24547
AXINAdapterCytosol6140.23.98353
AXLReceptorMembrane10105.70346
BADBcl2FamilyMitochondria121020.1060613.3855
BAG1AdapterCytosol20204.14003
BAKBcl2FamilyMitochondria21104.38056
BAP31AdapterER30304.2883
bARKKinaseCytosol6510.06666673.21087
BAXBcl2FamilyMitochondria6420.44.0939
BCL2Bcl2FamilyMitochondria10730.08888893.47941
BCLXLBcl2FamilyMitochondria6330.1333334.31631
BDNFLigandExtracellular20204.63756
BETA2ARReceptorMembrane63203.56178
BETAARRESTINAdapterCytosol8060.03571433.76112
BETACATENINTFCytosol12720.09090913.62603
BIDBcl2FamilyCytosol5320.34.23723
BIKBcl2FamilyCytosol22004.47117
BIMBcl2FamilyMitochondria3120.3333334.11038
BIPChaperoneER3110.6666675.81713
BR1RReceptorMembrane51404.26194
BRADYKININLigandExtracellular10105.2603
bRAFKinaseCytosol5410.13.63921
C3GGEFCytosol31204.10544
CADDNaseNucleus11005.4547
cADPRMessengerCytosol21104.4201
CAINInhibitorCytosol21104.09226
CALBINDINAdapterCytosol21003.95058
CALBRAINInhibitorCytosol10104.07084
CALCINEURINPhosphataseCytosol225160.05627713.13839
CALCIPRESSINInhibitorCytosol21104.13015
CALCIUMMessengerCytosol329190.03830653.03954
CALMODULINActivatorCytosol384320.03129453.01812
CALNEXINChaperoneER21003.99506
CALPAINProteaseCytosol6060.06666673.70016
CALRETICULINChaperoneER21003.99506
CAMKIKinaseCytosol5320.13.73806
CAMKIIKinaseCytosol295190.05172413.07249
CAMKIVKinaseCytosol9540.2222223.4201
CAMKKKinaseCytosol5230.13.52883
CAMKPASEPhosphataseCytosol30304.03954
cAMPMessengerCytosol131030.03846153.63756
CAMPGEFIIGEFCytosol21004.39374
CAPRIGAPCytosol21103.88633
CARM1TFNucleus10104.62438
CASAdapterCytosol4200.1666673.74794
CASKKinaseCytosol120903.54695
CASKINVesicleVesicles10004.5453
CASPASE3ProteaseCytosol197120.04678363.46129
CASPASE6ProteaseCytosol21104.76936
CASPASE7ProteaseCytosol7520.09523814.46787
CASPASE8ProteaseCytosol7430.09523813.91104
CASPASE9ProteaseCytosol10730.1777783.7743
CAVEOLINAdapterCytosol20014.26524
CB1RReceptorMembrane52304.26853
CB2RReceptorMembrane41304.27183
CBLUbiquitinaseCytosol9090.2777783.62768
CBPTFNucleus16650.08333333.32455
CDC42GTPaseCytosol10630.06666673.85173
CDGAPGAPCytosol3120.3333334.63756
CDK11KinaseCytosol10005.70346
CDK5KinaseCytosol6130.06666673.60132
CEK1KinaseCytosol21104.17298
CERAMIDELipidCytosol40403.60626
CFOSTFNucleus13910.1282054.00329
cGMPMessengerCytosol9540.02777784.37397
CHAPSYN110AdapterCytosol3000.6666673.86326
CHLORIDEIonCytosol11004.3196
CHOLESTEROLLipidMembrane10105.7117
cIAP1InhibitorCytosol20204.45634
cIAP2InhibitorCytosol20204.45634
CIPPAdapterCytosol4000.1666673.92092
CITRONKinaseCytosol11004.5173
CJUNTFNucleus211330.1047623.63427
CLATHRINVesicleVesicles5100.13.82372
CLIP170AdapterCytosol10004.55354
CMYCTFNucleus22004.25535
COFILINCytoskeletonCytosol54103.79077
COLLAGENMatrixExtracellular10104.9341
COMPLEXINVesicleVesicles20014.26524
COOLGEFCytosol6230.1333334.11203
CORTACTINCytoskeletonCytosol6220.1333333.74135
CPI17InhibitorCytosol64103.64086
CREDNANucleus22004.17628
CREBTFNucleus191450.07602343.26359
CREMTFNucleus4220.3333334.00824
CRIPTAdapterCytosol20004.04448
CRKAdapterCytosol9220.1666673.94893
CRMP2ActivatorCytosol21104.12356
CSKKinaseCytosol3030.6666674.04613
CSPAdapterCytosol3020.6666673.87315
CytochromeCActivatorMitochondria4220.1666674.20264
D1RReceptorMembrane52303.6458
D2RReceptorMembrane62403.69687
D3RReceptorMembrane51403.91269
DAGLipidCytosol5320.33.49918
DAPAdapterCytosol10004.42175
DAPKKinaseCytosol21103.84185
DARPP32InhibitorCytosol32103.70511
dATPMessengerCytosol10105.56672
DCP1RibosomeRibosomes20114.63427
DELTA_CATENINAdapterCytosol72203.95222
DENSINAdapterCytosol4000.53.6425
DGKKinaseCytosol21113.7743
DISHEVELEDAdapterMembrane31204.38386
DLKKinaseCytosol11004.68863
DMPKKinaseCytosol62403.92257
DNAJChaperoneER10005.92092
DNAPKKinaseNucleus11004.45964
DOC2VesicleVesicles32103.72323
DOKAdapterCytosol4210.3333333.99341
DOPAMINELigandExtracellular30304.27842
DOPRReceptorMembrane41304.27183
DREDNANucleus11004.65239
DREAMAdapterCytosol6130.06666673.65404
DYNAMINGTPaseVesicles15800.03809523.15486
DYNEINAdapterCytosol10004.2257
DYRKKinaseCytosol20204.27348
DYRK1AKinaseCytosol10104.15321
EEF1A2ElongationRibosomes11005.26689
EEF2GTPaseRibosomes11004.8402
EEF2KGTPaseRibosomes43103.84185
EFA6GEFCytosol10105.27677
EGFLigandExtracellular10104.40362
EGFRReceptorMembrane10450.1555563.40527
EIF1ARibosomeRibosomes10005.83361
EIF2RibosomeRibosomes54004.9687
EIF3RibosomeRibosomes3010.6666674.60297
EIF4ARibosomeRibosomes20014.63427
EIF4BRibosomeRibosomes10005.00165
EIF4EAdapterRibosomes6400.1333333.57166
EIF4GRibosomeRibosomes9200.1666673.83031
EIF5RibosomeRibosomes10105.96705
ELK1TFNucleus6410.23.89951
ENDOPHILINVesicleVesicles10004.15321
ENKEPHALINLigandExtracellular40404.84349
EPACGEFCytosol21104.4547
EPHB2ReceptorMembrane5140.14.35914
EPHRINLigandExtracellular10105.3575
EPS15AdapterCytosol3000.3333334.85008
EPS15RAdapterCytosol10005.19769
ERBBReceptorMembrane8130.07142863.84679
ERBINAdapterCytosol3000.3333334.17957
ERK5KinaseCytosol11007.88962
EZRINCytoskeletonCytosol11005.514
FADDAdapterCytosol32104.8089
FAKKinaseCytosol9240.1111113.46952
FASReceptorMembrane21105.80395
FASCINCellAdhesionMembrane31003.62932
FASLLigandExtracellular10106.80231
FBW7UbiquitinaseCytosol20204.62932
FERKinaseCytosol10104.62438
FHL2TFNucleus20214.60297
FIBRINOGENLigandExtracellular10104.9341
FIBRONECTINMatrixExtracellular10104.9341
FILAMINCytoskeletonCytosol21003.76606
FIVEHT1ARReceptorMembrane51404.17628
FIVEHT1CRReceptorMembrane11006.15321
FIVEHT2ARReceptorMembrane31204.27018
FIVEHT4RReceptorMembrane31204.27348
FKBPAdapterCytosol3010.3333333.90939
FLIPInhibitorCytosol10104.90939
FORKHEADTFNucleus22004.13015
FOSBTFNucleus3000.6666674.62932
FOUREBP1TFNucleus3210.3333334.03954
FOXO3ATFNuclleus11004.48435
FRA1TFNucleus3000.6666674.62932
FRA2TFNucleus3000.6666674.62932
FRAT2AdapterCytosol10004.25865
FRIZZLEDReceptorMembrane4400.1666674.74959
FRKKinaseCytosol10105.00165
FYNKinaseCytosol15660.06666673.32784
GAB1AdapterCytosol4210.53.89621
GABALigandExtracellular21105.02636
GABAARReceptorMembrane75103.32125
GABABRReceptorMembrane31204.28007
GABARAPAdapterCytosol3000.3333334.01812
GAIPGAPCytosol10104.96211
GALPHA11GproteinCytosol6510.06666674.06425
GALPHA12GproteinCytosol10105.21582
GALPHA13GproteinCytosol30304.60461
GALPHAIGproteinCytosol222020.0043293.86326
GALPHAOGproteinCytosol1515003.98188
GALPHAQGproteinCytosol121110.01515153.96376
GALPHASGproteinCytosol85304.09061
GALPHAZGproteinCytosol53203.81713
GAP43AdapterCytosol21103.59802
GAT1TransporterMembrane31104.35585
GBETAGAMMAGproteinCytosol4230120.008130083.28995
GDNFLigandExtracellular10104.84514
GELSOLINCytoskeletonCytosol5320.33.79077
GEPHYRINAdapterMembrane3000.3333334.02471
GIRKChannelMembrane43103.76277
GIT1AdapterCytosol10005.11038
GKAPAdapterCytosol20104.16145
GLUTAMATELigandExtracellular50503.71005
GLYCINELigandExtracellular31203.9341
GLYRReceptorMembrane54003.44646
GLYT1TransporterMembrane10104.93245
GRABGEFCytosol20104.80231
GRB10AdapterCytosol32104.25535
GRB2AdapterCytosol23880.07509883.33114
GRIPAdapterCytosol50003.72982
GRITGAPCytosol6230.23.98023
GRP94ChaperoneER10005.92092
GSK3KinaseCytosol165100.0753.2603
H2O2MessengerCytosol21105.12521
HCKKinaseCytosol10104.16145
HDAC3HdacNucleus10104.63262
HIPK2KinaseCytosol10105.70346
HIPPOCALCINAdapterCytosol21103.92092
HOMERAdapterCytosol60103.69687
HRS2VesicleVesicles10104.52059
I1InhibitorCytosol32103.70511
IBP1AdapterVesicles20004.59967
IBP2AdapterVesicles20004.57661
ICA512ReceptorMembrane10004.47941
ICADInhibitorCytosol21104.45634
IGF1LigandExtracellular10105.00824
IGF1RReceptorCytosol61404.00988
IKBAInhibitorCytosol4210.1666674.48764
IKBBAdapterCytosol10104.72652
IKKAKinaseCytosol3200.6666674.78748
IKKBKinaseCytosol32104.92257
ILKKinaseCytosol5230.23.8056
INHIBITOR2InhibitorCytosol32103.91928
INSULINLigandExtracellular10105.16145
INTEGRINCellAdhesionMembrane105203.93575
IP3LipidCytosol32103.78089
IP3RChannelER9510.08333333.37562
IP6K2KinaseCytosol10005.80066
IQGAPGAPCytosol7110.0476193.55519
IRReceptorMembrane52304.1631
IRS1AdapterCytosol13830.06410263.17792
IRS2AdapterCytosol32104.20593
ITSN1AdapterVesicles8130.1071434.21252
ITSN2AdapterVesicles10005.84843
JAKKinaseCytosol21104.38221
JIPAdapterCytosol12380.0303033.69028
JNKKinaseNucleus15690.0476193.53871
JUNBTFNucleus5000.44.59802
JUNDTFNucleus5000.44.59802
KALIRINGEFCytosol21104.60461
KARChannelMembrane9400.02777783.4201
KChIP1AdapterCytosol20004.01812
KChIP2AdapterCytosol20003.85338
KChIP4AdapterCytosol20103.85338
KINESINCytoskeletonCytosol20004.5832
KIR21ChannelMembrane3010.3333334.23723
KIR23ChannelMembrane31103.7397
KIR41ChannelMembrane20104.60626
KOPRReceptorMembrane41304.27183
KSRKinaseCytosol4010.53.78583
KV11ChannelMembrane3210.3333333.98847
KV12ChannelMembrane31104.14333
KV14ChannelMembrane10104.98682
KV41ChannelMembrane31104.09226
KV42ChannelMembrane74103.50906
KV43ChannelMembrane20104.63427
L1CellAdhesionMembrane40204.51565
LAMINACytoskeletonNucleus11005.76771
LARGGEFCytosol20104.36244
LCKKinaseCytosol6230.06666673.77595
LEFTFNucleus3210.3333334.59473
LIMKKinaseCytosol32104.23723
LRPReceptorMembrane21115.74629
LTYPECAChannelMembrane12710.1363643.13509
LYNKinaseCytosol4020.3333333.83361
M1RReceptorMembrane5130.24.26194
M2RReceptorMembrane5130.14.2603
M4RReceptorMembrane41304.26853
MADDAdapterCytosol11007.46129
MALSAdapterCytosol20013.87315
MAP1ACytoskeletonCytosol21004.04448
MAP1BActivatorCytosol10004.2257
MAP2CytoskeletonCytosol7500.1904763.28007
MAPKKinaseCytosol257170.023.36244
MAPKAPK2KinaseCytosol22004.30313
MARCKSAdapterCytosol43003.40198
MBPCytoskeletonCytosol11003.78583
MDM2UbiquitinaseNucleus10104.33773
MEF2TFNucleus44003.98847
MEK1KinaseCytosol6320.23.85338
MEK2KinaseCytosol20204.3575
MEK3KinaseCytosol43104.4827
MEK4KinaseCytosol4400.1666674.41845
MEK5KinaseCytosol21106.89127
MEK6KinaseCytosol21104.76771
MEK7KinaseCytosol21114.32619
MEKK1KinaseCytosol6240.1333334.26853
MEKK2KinaseCytosol10105.4168
MEKK3KinaseCytosol10105.48105
MEKK4KinaseCytosol31204.8682
MERLINAdapterCytosol10004.96705
MGLUR1ReceptorMembrane72403.52059
MGLUR5ReceptorMembrane30203.80395
MGLUR7ReceptorMembrane11630.01818183.229
MINTVesicleVesicles20004.29489
MITFTFNucleus22004.25041
MKP1PhosphataseCytosol30304.10708
MKP2PhosphataseCytosol20204.12685
MKP5PhosphataseCytosol20204.41186
MLCKKinaseCytosol32103.83526
MLK3KinaseCytosol5320.13.97035
MNK1KinaseCytosol4210.1666674
MOPRReceptorCytosol6330.06666673.85502
MP1AdapterCytosol20214.29984
mRNARNARibosomes9100.1666674.00329
MSK1KinaseCytosol32104.00329
MST3AdapterCytosol11003.92586
MTORKinaseCytosol5140.14.12026
MUNC13VesicleVesicles43103.71005
MUNC18VesicleVesicles4200.1666673.61614
MUPP1AdapterCytosol20113.99835
MUSKKinaseCytosol11004.1911
MUSKELINAdapterCytosol10005.70346
MYOSINCytoskeletonCytosol33004.6804
MYOSINVCytoskeletonCytosol20113.82702
MYPT1PhosphataseCytosol32104.62768
MYPT2PhosphataseCytosol32104.42504
N41AdapterCytosol5110.23.81549
NAIPInhibitorCytosol4130.3333334.23064
NAKEDAntagonistCytosol10105.74794
NASCENTCHAINPeptideRibosomes8200.03571434.92257
NCADHERINCellAdhesionMembrane20104.32455
NCKAdapterCytosol6220.1333333.77759
NCS1AdapterCytosol11004.03789
NELigandExtracellular30304.53213
NEURABINAdapterCytosol10004.48929
NEUREXINCellAdhesionMembrane20014.85008
NEUROFIBROMINGAPCytosol10104.37068
NEUROGRANINInhibitorCytosol21103.59802
NEUROLIGINCellAdhesionMembrane4000.1666674.40527
NFATTFNucleus7700.0476193.39209
NFHCytoskeletonCytosol33003.9028
NFKBTFNucleus4310.1666673.72817
NFMCytoskeletonCytosol11004.36079
NGFLigandExtracellular20204.45634
NHERFAdapterCytosol30004.05766
NIKKinaseCytosol6040.06666674.20264
NMDARReceptorMembrane301130.07586212.94399
NOMessengerCytosol21104.19934
NOPRReceptorMembrane41304.27183
NOSSynthaseCytosol11810.07272733.21087
NRCAMCellAdhesionMembrane10004.80395
NRGLigandExtracellular10104.84514
NT4LigandExtracellular10104.7397
NTYPECAChannelMembrane7610.2857143.32784
Nup214CytoskeletonNucleus10004.53707
NWASPActivatorCytosol7420.09523813.64086
P1433AdapterCytosol143100.05494513.486
P38KinaseCytosol176110.01470593.81713
P53TFNucleus10900.04444443.33937
P75NTRReceptorMembrane62405
PAMessengerCytosol30303.84679
PABPAdapterRibosomes20014.63427
PAC1PhosphataseCytosol20204.30313
PAFLigandExtracellular10105.2603
PAFRReceptorMembrane51404.26194
PAKKinaseCytosol10360.06666673.55354
PAR1AdapterCytosol11005.38221
PAR2ReceptorMembrane42204.10873
PARPPolymeraseCytosol11004.45964
PAXILLINAdapterCytosol6200.1333334.01318
PCAFTFNucleus11004.3229
PDE1APDECytosol21103.99012
PDE1BPDECytosol21103.99012
PDE1CPDECytosol21103.99012
PDE2APDECytosol21104.60461
PDE3APDECytosol3210.3333333.88468
PDE3BPDECytosol3210.3333333.88468
PDE4APDECytosol10104.63591
PDE4BPDECytosol10104.63591
PDE4CPDECytosol10104.63591
PDE4DPDECytosol3210.3333333.80395
PDE5APDECytosol3210.3333333.89456
PDGFLigandExtracellular10104.94728
PDGFRReceptorMembrane51303.94893
PDIChaperoneER10105.92092
PDK1KinaseCytosol5140.23.5453
PDZGEFGEFCytosol20204.5832
PERKKinaseCytosol10105.96705
pGCCyclaseCytosol32105.03954
PHAPActivatorCytosol10105.56672
PHASInhibitorRibosomes21104.47776
PHOSPHOLAMBANPumpER21103.93575
PI3KKinaseCytosol151120.05714293.30148
PICCOLOAdapterCytosol10004.72817
PICK1AdapterCytosol5010.33.51236
PIN1TFNucleus3030.3333334.16474
PIP2LipidCytosol205150.03684213.16639
PIP3LipidMembrane9270.08333333.36903
PIP5KKinaseCytosol3210.3333333.84679
PKAKinaseCytosol512460.0125492.92751
PKBKinaseCytosol14770.07692313.30972
PKCKinaseCytosol506390.01469392.78748
PKCEKinaseCytosol10004.48929
PKCZETAKinaseCytosol31205.89621
PKDKinaseCytosol10104.48435
PKGKinaseCytosol6150.06666673.80395
PKIInhibitorCytosol10103.92586
PKNKinaseCytosol10104.63921
PKRKinaseCytosol4310.1666674.41186
PLA2PhospholipaseCytosol4310.1666673.57825
PLCBETAPhospholipaseCytosol10730.02222223.13509
PLCGAMMAPhospholipaseCytosol161130.0753.1631
PLDPhospholipaseCytosol32003.85667
PMCAPumpMembrane6510.1333333.1944
POTASSIUMIonCytosol1010003.98847
PP1PhosphataseCytosol13660.05128213.46458
PP2APhosphataseCytosol184140.05882353.23888
PP2CPhosphataseCytosol10104.38386
PP5PhosphataseCytosol10104.31137
PQCaChChannelMembrane7210.2857143.3575
PRESENILINProteaseMembrane5100.23.8089
PRK2KinaseCytosol11005.35585
PRMT1MethylaseCytosol10104.36903
PROFILINCytoskeletonCytosol6120.1333333.52224
PSD93AdapterCytosol4000.1666673.72652
PSD95AdapterCytosol27110.0256413.42339
PTENPhosphataseCytosol31203.90939
PTP1BPhosphataseCytosol10105.16145
PTP1DPhosphataseCytosol10003.94234
PTPAPhosphataseCytosol41303.88962
PYK2KinaseCytosol6240.06666673.8369
RAB3GTPaseVesicles5500.13.80725
RABGDIInhibitorCytosol10104.8056
RABPHILINVesicleVesicles7510.1904763.2883
RACGTPaseCytosol13930.01282053.8056
RACKAdapterCytosol6010.23.44152
RADIXINAdapterCytosol21004.44316
RAF1KinaseCytosol151230.05714293.21746
RAIAdapterCytosol11004.84514
RALGTPaseCytosol21105.00824
RALBP1GAPCytosol51204.52554
RALGDSGEFCytosol4310.1666674.18616
RANGTPaseNucleus11005.70346
RANBPMAdapterCytosol115104.70511
RAP1GTPaseCytosol12930.0303033.6425
RAP1GAPGAPCytosol10104.64086
RAP2GTPaseCytosol3120.3333334.35255
RASGTPaseCytosol171340.02941183.37232
RASGAPGAPCytosol6320.06666673.51071
RASGRFGEFCytosol7420.2380953.3575
RASGRPGAPCytosol4310.3333333.56178
RASGRP3GEFCytosol31203.61779
RBTFNucleus11004.45964
RCSInhibitorCytosol43103.54201
REELINLigandExtracellular10104.9341
REPS1AdapterCytosol30004.25206
RETReceptorMembrane6220.23.84679
RGS2GproteinCytosol5030.34.58979
RGS4GAPCytosol10104.96211
RHEBAdapterCytosol31204.14003
RHOGTPaseCytosol106303.51895
RHOGEFGEFCytosol42104.21746
RICAdapterCytosol11004.01647
RICSAdapterCytosol11004.07084
RIMAdapterVesicles8160.1071433.51565
RINActivatorCytosol3210.3333333.73641
RIPKinaseCytosol21106.44975
ROCKKinaseCytosol71603.97199
RSKKinaseCytosol62403.78913
RTYPECAChannelMembrane21113.96376
RYRChannelER8610.1071433.44152
S40RibosomeRibosomes6100.1333334.83526
S6AdapterRibosomes32104.68369
S60RibosomeRibosomes3010.3333335.75947
S6KKinaseCytosol62404.10049
SAM68AdapterCytosol9410.08333333.37068
SAP102AdapterCytosol21003.85997
SAP97AdapterCytosol5110.33.65239
SAPAPAdapterCytosol10004.93245
SEC61PChannelER6300.25.49753
SEC63PAdapterER20216.49423
SEKKinaseCytosol11005.26689
SEQUESTOSOMEAdapterCytosol21106.75618
SEROTONINLigandExtracellular40405.15486
SHANKAdapterCytosol40104.32125
SHCAdapterCytosol15820.1619053.57661
SHP1PhosphataseCytosol8340.07142863.65404
SHP2PhosphataseCytosol7250.1904763.47941
SIAHAdapterCytosol10104.63921
SIVA1AdapterCytosol10105.31466
SKYReceptorMembrane10105.70346
SMACDIABLOInhibitorMitochondria32105.37397
SNAP25VesicleVesicles12510.1515153.52224
SNAPINVesicleVesicles31203.69357
SOD1DismutaseCytosol10106.12356
SODIUMIonCytosol42203.93575
SORCINAdapterCytosol4110.3333333.68369
SOSGEFCytosol5310.13.89951
SPALGAPCytosol20104.16474
SPECTRINCytoskeletonCytosol8300.1428573.48105
SPHKKinaseCytosol11004.95058
SPINOPHILINCytoskeletonCytosol4210.1666673.61779
SPROUTYAdapterCytosol3200.6666674.06425
SRCKinaseCytosol256160.053.19275
SRCASMAdapterCytosol31103.82043
SREDNANucleus3100.6666674.39539
SRFTFNucleus5300.23.56178
SRP54AdapterRibosomes31205.81878
SRPRReceptorER21106.49259
SSLigandExtracellular20205.11367
SSCAMAdapterCytosol30003.9341
SSTR1ReceptorMembrane41304.27183
SSTR2ReceptorMembrane51404.11862
STARGAZINChaperoneCytosol20004.02801
STATTFNucleus32004.1944
STAT1TFNucleus10004.3229
STAT5TFNucleus10004.3229
STEPPhosphataseCytosol32103.62438
STONIN2AdapterVesicles5000.24.19934
SUMO1SumoCytosol3030.3333334.16474
SUMO2SumoCytosol20214.60297
SUMO3SumoCytosol20214.60297
SURVIVINAdapterCytosol10106.37232
SV2AVesicleVesicles21113.96376
SYKKinaseCytosol5220.33.81878
SYNAPSINVesicleVesicles14820.0439563.09885
SYNAPTOBREVINVesicleVesicles3000.3333334.25206
SYNAPTOPHYSINVesicleVesicles31004.71334
SYNAPTOTAGMINVesicleVesicles11430.1818183.47446
SYNDECANReceptorMembrane21004.76606
SYNGAPGEFCytosol5220.13.73641
SYNTABULINAdapterCytosol20004.17463
SYNTAPHILINVesicleVesicles10104.4514
SYNTAXINVesicleVesicles18820.09150333.45305
SYNTENINAdapterCytosol50003.9687
SYNTROPHINAdapterCytosol11004.84514
TALINCytoskeletonCytosol3000.3333334.4168
TAMALINAdapterCytosol31104.01647
TAUActivatorCytosol11900.03636363.31301
TBR1TFNucleus11004.5453
TCFTFNucleus6220.43.97199
TFIIBTFNucleus11004.26194
TFIIDTFNucleus11004.26194
THCLigandExtracellular10105.26689
TIAM1GEFCytosol42103.49423
TNFALPHALigandExtracellular10107.46129
TNFR1ReceptorMembrane31206.46293
TNIKKinaseCytosol30104.32619
TRADDAdapterCytosol41305.47117
TRAF2AdapterCytosol42004.93575
TRAF4AdapterCytosol11005.99835
TRAF6AdapterCytosol11005.99835
TREDNANucleus11005.24382
TRKAReceptorMembrane8170.253.55519
TRKBReceptorMembrane62403.74135
tRNARNARibosomes10005.96705
TRYPSINProteaseExtracellular10105.10708
TSCGAPCytosol21104.30148
TUBERINGAPCytosol10104.64086
TUBULINCytoskeletonCytosol20610.03684213.22735
TWA1AdapterCytosol10005.70346
USP11HydrolaseCytosol10005.70346
VAMPVesicleVesicles21013.82702
VASPAdapterCytosol10004.52059
VAVGEFCytosol131030.06410263.64086
VDAC2ChannelMitochondria10105.37891
VILIPAdapterCytosol11004.03789
VINCULINCytoskeletonCytosol20014.47117
VITRONECTINMatrixExtracellular10104.9341
VRK1KinaseCytosol10105.24382
WNTLigandExtracellular20215.74629
XIAPInhibitorCytosol4130.3333334.38221
YESKinaseCytosol10004.42175
YOTIAOAdapterCytosol3000.6666673.55684
ZAP70KinaseCytosol20204.08072