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Case
#16:
Clinical Presentation:
A 24 year-old man with a history of Systemic Lupus Erythematosis
presents with disseminated pustulo-nodular skin lesions (Case 16
Image 1). His medications include Prednisone 20mg daily. Bacterial
cultures of the lesions had no growth. Unroofed lesions exuded copious
amounts of thick yellow exudate.
Clinical Diagnoses:
Staphylococcal pyoderma
Disseminated Herpes virus
Mycosis Fungoides (Cutaneous T Cell Lymphoma)
Nontuberculous Mycobacterial Infection
Systemic Mycoses
Case 16 Image 2: Giemsa stain of scrapings showing septate hyphae
coursing through exudate.
Case 16 Image 3: Gram stain showing outline of fungal hyphae accentuated
by purulent exudate abutting and delineating the hyphae.
Discussion:
Microbiologic Diagnosis:
Invasive Tricophyton Rubrum
This dermatophyte fungus can cause deep follicular invasive as well
as systemic invasion in individuals who are immunosuppressed. Transmitted
from person to person by direct contact and also soil to human.
On Sabouraud's media (Case 16 Image 4) colonies of Tricophyton rubrum
are cottony and powdery. A reddish-purplish pigmentation develops
on the underside of the colony.
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