Volume 65 Number 4 September 1998	back to contents

Severe Hyponatremia, Neuroleptic Malignant Syndrome, Rhabdomyolysis	284
and Acute Renal Failure: A Case Report Cristina Elizalde-Sciavolino, Alex Racco, Tamie Proscia-Lieto, and Morton Kleiner

ABSTRACT
Acute renal failure secondary to myoglobinuria is a rare yet possible complication of malignant neuroleptic syndrome associated with the use of dopamine antagonists. We describe the case of a 42-year-old schizophrenic man who presented with severe hyponatremia, and proceeded to acute malignant neuroleptic syndrome, rhabdomyolysis, and acute renal failure. We contend that the acute hyponatremia may have served as a precipitating factor.

KEY WORDS
hyponatremia, psychogemic polydipsia, inappropriate secretion of antiduretic hormone, neuroleptic malignant syndrome, rhabdomyolysis, acute renal failure

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