Mount Sinai Journal of Medicine - Volume 66, Number 2, Page 128

Volume 66 Number 2
March 1999 back to contents

Mortality Associated with Concurrent Strongyloidosis and Cytomegalovirus Infection
in a Patient on Steroid Therapy 128 - 132

Beverly Y. Wang, M.D.¹, Sashikala Krishnan, M.D.², And Henry D. Isenberg, Ph.D.³

From the Department of Pathology, Mount Sinai School of Medicine, New York, NY. ¹Department of Pathology, Elmhurst Medical Center, Elmhurst, NY; and Departments of ²Pathology and ³Clinical Microbiology, Mount Sinai School of Medicine of Medicine, New York, NY.
Address correspondence to Henry D. Isenberg, Ph.D., Professor of Clinical Microbiology, Center for Clinical Laboratories, Box 1122, Mount Sinai School of Medicine, One East 100th Street, New York, NY 10029.

ABSTRACT
Disseminated strongyloidosis has been recognized with increasing frequency, often in patients who are immunocompromised or have received steroid therapy. In addition, disease due to cytomegalovirus (CMV) is noted in immunodeficient hosts. We report on a 55-year-old Puerto Rican man who received steroid treatment for oropharyngeal pemphigus vulgaris and developed abdominal symptoms with alternating constipation and diarrhea. The clinical work-up did not reveal specific abnormalities, but the patient died of cardiopulmonary failure. At the postmortem examination, the patient had evidence of strongyloidosis and CMV disease. This report reviews both this case and the literature, and discusses the overlapping infections of strongyloidosis and CMV disease in this patient who had received steroid therapy.

KEY WORDS
Disseminated strongyloidosis, autoinfection, cytomegalovirus, steroid therapy, cardiopulmonary failure

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Mortality Associated with Concurrent Strongyloidosis and Cytomegalovirus Infection in a Patient on Steroid Therapy	128 - 132
Beverly Y. Wang, M.D.¹, Sashikala Krishnan, M.D.², And Henry D. Isenberg, Ph.D.³
From the Department of Pathology, Mount Sinai School of Medicine, New York, NY. ¹Department of Pathology, Elmhurst Medical Center, Elmhurst, NY; and Departments of ²Pathology and ³Clinical Microbiology, Mount Sinai School of Medicine of Medicine, New York, NY. Address correspondence to Henry D. Isenberg, Ph.D., Professor of Clinical Microbiology, Center for Clinical Laboratories, Box 1122, Mount Sinai School of Medicine, One East 100th Street, New York, NY 10029.