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| Volume 67 Number
5&6 October & November 2000 |
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| Effects of LAAM and Methadone Utilization in an Opiate Agonist Treatment Program | 398-403 |
Juan F. Valdivia, M.D. and Samina Khattak, M.D. |
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| Address correspondence to Dr. Juan F. Valdivia, Chief, Drug Dependency Treatment Program, Building 228, Mail Code 116c, Hines Veterans Administration Hospital, Hines, IL 60141. |
ABSTRACT
The development and approval of levo-alpha-acetylmethadol (LAAM) as a pharmacotherapeutic
agent in opioid agonist therapy provided an alternative to methadone. Clinicians
recognized the potential benefits that LAAM, a synthetic mu agonist with pharmacological
properties which differ from those of methadone, could have in the treatment
management of addicts in opioid agonist therapy. We report our experience utilizing
LAAM from 1995 to 1999 at the Hines VA opioid agonist therapy clinic. The addition
of LAAM to the clinic’s treatment armamentarium has resulted in management options
that have improved the areas of patient recruitment, patient retention, patient
traffic, take-home medication, detoxification, and treatment outcomes
KEY WORDS
LAAM,
methadone,
opiate
addiction, opioid
replacement therapy
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