The Mount Sinai Journal of Medicine - Mount Sinai School of Medicine

Volume 70 Number 6 November 2003	back to contents

Drug-Eluting Stents in Peripheral Vascular Disease: Eliminating Restenosis	417-419
Sharif H. Ellozy, M.D., and Alfio Carroccio, M.D.

Assistant Professor of Surgery, Division of Vascular Surgery, Department of Surgery, Mount Sinai School of Medicine, New York, NY.

Address all correspondence to Sharif H. Ellozy, M.D., Department of Surgery, Mount Sinai School of Medicine, One East 100th Street, New York, NY 10029; e-mail: sharif.ellozy@msnyuhealth.org

ABSTRACT

Transcatheter endovascular therapy for peripheral atherosclerotic disease has become more popular. In general, good results have been reported in focal aortoiliac disease. However, the long-term patency of angioplasty in longer, more distal lesions has been less satisfactory. Stenting has not been shown to improve long-term patency compared to angioplasty alone. Drug-eluting stents have shown promise in preventing coronary restenosis, and preliminary results in peripheral arterial disease are encouraging. This review article will discuss the current status of endovascular therapy of aortoiliac and femoropopliteal atherosclerotic disease, the theoretic and experimental basis for the use of drug-eluting stents, and the preliminary results in human studies.

KEY WORDS

Drug-eluting stents, peripheral artery occlusive disease, restenosis.

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