The Mount Sinai Journal of Medicine

 

Volume 73 Number 5
September 2006
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Aortic Occlusion in Patients Treated with Cisplatin-Based Chemotherapy 810-812
Tal Grenader, M.D.¹, Linda Shavit, M.D.², Inna Ospovat, M.D.¹, Orit Gutfeld, M.D.¹, and Tamar Peretz, M.D.¹

From the ¹Department of Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel; and ² Department of Medicine, Sha'are Zedek Medical Center, Jerusalem, Israel.

Address all correspondence to Tal Grenader, M.D., Sharett Institute of Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel, 91120; e -mail: talgrenader65@hotmail.com

Accepted for publication October 2005.

Abstract

Cisplatin-based chemotherapy is one of the most common chemotherapy regimens that is complicated by thromboembolic events. A wide spectrum of vascular events exists, including venous and arterial thromboses of varying severity and location. However, total occlusion of the aorta is very unusual. We describe two patients with atherosclerotic vascular disease who developed occlusion of the abdominal aorta after cisplatin-based chemotherapy.

Key Words

Cisplatin-based chemotherapy, thrombosis, aorta, peripheral vascular disease.


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