Department of Structural and Chemical Biology

Message from the Chair

The Department of Structural and Chemical Biology develops and employs powerful tools and technologies of experimental and computational structural biology, biophysics, and chemical biology to the fundamental problems of the molecular basis and mechanisms of human biology and disease. The Department consists of diverse and synergistic research programs with an active development plan to recruit new faculty both in structural and chemical biology. Scientists in the Department study three-dimensional atomic structure, molecular function and regulation of biological macromolecules and complexes, as well as design and develop novel small-molecule chemicals to advance basic and translational research. Topics of investigation include structure and function of cell membrane-bound ion channels and receptors in cardiology and cell development; and molecular mechanisms of gene transcription and translation, epigenetic regulation and DNA damage repair in stem cell biology, immunology and virology with ultimate goals to understand the molecular basis of human diseases such as cancer, Alzheimer's disease and genetic disorders. The research and academic training in the Department is supported by state-of-the-art shared research resources in structural and chemical biology, and facilitated by regular research seminars and conferences at Mount Sinai School of Medicine. The Department is committed to providing a nurturing environment for discovery and innovation in basic and translational biomedical research of human biology and disease, and for advanced academic training of physicians and scientists; and to functioning as a scientific hub for interdisciplinary collaborations with researchers of different disciplines to tackle most challenging problems in biomedical sciences.

Ming-Ming Zhou, Ph.D.
Professor & Chair, Structural And Chemical Biology
Professor, Oncological Sciences
Professor, Pharmacology And Systems Therapeutics

Contact Information

Department of Structural and Chemical Biology
Mount Sinai School of Medicine
One Gustave L. Levy Place
New York, NY 10029
Box 1677
Tel: (212) 659-8647
Fax: (212) 849-2456