Greg Holmes

Greg Holmes, PhD

  • ASSISTANT PROFESSOR | Genetics and Genomic Sciences

Dr Greg Holmes received his PhD from The University of Queensland, Australia. In the laboratory of Dr Melissa Little, he characterized protein-DNA and protein-protein interactions of the Wilms’ tumor suppressor gene 1 (WT1) zinc-finger protein and the effect of Denys-Drash syndrome mutations on WT1 DNA binding. His postdoctoral training has been in the laboratories of Lee Niswander (Memorial Sloan-Kettering Cancer Center, NY) studying chick and mouse embryological limb development, and Claudio Basilico (NYU School of Medicine, NY) studying inhibitory interactions of the Fgf signaling pathway on the Wnt signaling pathway, including the role of Sox2, in osteoblasts. While there, he developed a strong interest in craniofacial development, studying a mouse model of the Apert craniosynostosis syndrome. He joined the Jabs lab as an Instructor in 2011 to pursue further research into the molecular processes and tissue interactions underlying a variety of craniosynostosis syndromes.

Education

BSc (Hons), Sydney University

PhD, University of Queensland