Dr. Erblich's research focuses on the interactions among emotional, cognitive, behavioral and genetic factors in cancer prevention and control. Current efforts focus on nicotine dependence and alcoholism. Dr. Erblich's research takes a multidisciplinary-translational approach, with hypotheses driven by both the human and animal literatures that have contributed to the current understanding of motivations for drug use. The overall goal of Dr. Erblich's research in this area is to better understand how cognitive-behavioral, affective, and genetic factors impact smoking behavior. The research thus draws upon behavioral principles, such as personality, conditioning, and stress reactivity, as well as molecular biological principles, including genetic and cellular mechanisms of dopamine transmission to better understand motivation for substance use. Dr. Erblich is also a trained biostatistician and collaborates on a diverse portfolio of NIH-funded projects in cancer prevention and control, as well as projects that focus on the intergation of behavior and health more broadly.