Olga Camacho-Vanegas, PhD
ASSISTANT PROFESSOR | Genetics and Genomic Sciences
ASSISTANT PROFESSOR | Genetics and Genomic Sciences
Research
Our Laboratory involve in a number of translational research projects. In particular we are focused on human gene discovery projects with a particular interest in tumor suppressor genes, the generation of animal model for understanding the biological role of these genes in cancer and ultimately the generation of novel therapeutic targets to cure cancer.
Among the projects running in our laboratory, I am leading the project: Linkage analysis and gene descovery for a novel bone dysplasia/cancer syndrome linked to chromosome 9p21-22:DMS-MFH (Diaphyseal medullary stenosis (sclerosis) with bone malignancy (malignant fibrous histiocytoma): Hardcastle syndrome, Malignant fibromatosis)". Throught linkage analysis, we have narrow the disease region to 1.6 Mb and have a identified a very interesting candidate gene. At present, we are in the process to demostrate the discovery a "new tumor suppressor gene". The use of in vivo and in vitro experimental strategies will help us to establish the function of the novel gene and to define the underlying disease mechanisms.
Another project in which I am actively participating is aimed to define the role and the molecular mechanisms by which of the Kruppel-like factor (KLF6) tumor suppressor gene and its KLF6-SV1 splice variant in human cancer.
Among the projects running in our laboratory, I am leading the project: Linkage analysis and gene descovery for a novel bone dysplasia/cancer syndrome linked to chromosome 9p21-22:DMS-MFH (Diaphyseal medullary stenosis (sclerosis) with bone malignancy (malignant fibrous histiocytoma): Hardcastle syndrome, Malignant fibromatosis)". Throught linkage analysis, we have narrow the disease region to 1.6 Mb and have a identified a very interesting candidate gene. At present, we are in the process to demostrate the discovery a "new tumor suppressor gene". The use of in vivo and in vitro experimental strategies will help us to establish the function of the novel gene and to define the underlying disease mechanisms.
Another project in which I am actively participating is aimed to define the role and the molecular mechanisms by which of the Kruppel-like factor (KLF6) tumor suppressor gene and its KLF6-SV1 splice variant in human cancer.
Education
PhD, University of Rome
Office Locations
Industry Relationships
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Camacho-Vanegas has not yet completed reporting of Industry relationships.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.
Dr. Camacho-Vanegas has not yet completed reporting of Industry relationships.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.