Institute for Personalized Medicine 

Erwin P. Böttinger, MD
Director of the Charles R. Bronfman Institute for Personalized Medicine, Irene and Dr. Arthur Fishberg Chair and Professor in Medicine, and Professor of Pharmacology and Systems Therapeutics

When it comes to treatments for diseases and conditions, physicians are learning that one size does not fit all. As Director of the Charles R. Bronfman Institute for Personalized Medicine, Erwin P. Böttinger, MD, believes that the future of medicine relies on developing more tailored and targeted approaches for treating acute and chronic diseases and conditions.

The core programs of the Institute include clinical and translational genomics, biomedical informatics, biobanking and biorepositories, and core technologies and services. Institute researchers are exploring how an individual’s vulnerability to illness and responsiveness to therapeutics are influenced by genetic information and environmental exposure. This customized model of genome-informed health care promises to dramatically advance clinical practice as well as the delivery and economics of health care.

An expert in kidney disease, Dr. Bottinger has been devoted to developing genome-informed models in his own research. In an effort to help the millions of Americans with chronic diabetic and non-diabetic kidney diseases that cause kidney failure, Dr. Bottinger is the principal investigator of an NIH-funded personalized medicine program aimed at identifying and validating molecular biomarkers that can better predict progressive kidney disease in humans.

Dr. Bottinger was previously an Associate Professor of Medicine and Molecular Genetics at Albert Einstein College of Medicine in Bronx, New York, for six years. During his tenure at Albert Einstein he also held several hospital appointments, including Attending Physician in the Department of Medicine at Montefiore Medical Center and Jacobi Medical Center in the Bronx. Dr. Bottinger also served as Visiting Associate at the National Cancer Institute and Visiting Staff Physician in the Kidney Disease Section at the Warren Grant Magnuson Clinical Research Center of the National Institutes of Health in Bethesda, Maryland.

Dr. Bottinger has published many scientific studies and has received several awards, including the Special Service Award from the National Cancer Institute and the Mellini Award for Excellence in Biomedical Sciences. In 2002, he was elected a member of the American Society for Clinical Investigation.

Trained in Europe, Dr. Bottinger received his medical degree from Friedrich-Alexander Universitat School of Medicine in Erlangen, Germany. He moved to New York to pursue a residency in internal medicine at Cabrini Medical Center and later completed a clinical and research fellowship in nephrology at Massachusetts General Hospital and Harvard Medical School in Boston. In addition, he served as a research fellow at the National Cancer Institute, where he stayed on as a Visiting Associate for four more years. Dr. Bottinger joined Mount Sinai in 2004.