Simonyan Laboratory

Hierarchical Organization of the Central Voice Control

Brain networks responsible for (I) laryngeal, articulatory and respiratory coordination, (II) vocalization initiation and motivation, (III) voluntary vocal motor control. Read More

Larynx Motor Area Projects to the Striatum

The projection fields of the laryngeal motor cortex to the putamen and caudate nucleus in the rhesus monkey, Macaca mulatta. Read More

Brain Activation During Laryngeal Tasks

Brain regions of common activation during voluntary coughing, sniffing and breathing in healthy humans. Read More

Brain Networks Controlling Human Voice and Breathing

Common and distinct functional and structural brain networks of the laryngeal motor cortex during voluntary production of syllables and breathing in healthy humans. Read More

Larynx Area of the Motor Cortex

Larynx representation within the motor cortex in humans (A,C) and non-human primates (B,D). Read More

Brainstem Pathology in Spasmodic Dysphonia

Normal brainstem cell morphology (I) is associated with microglia activation (II) in the solitary tract nucleus. Read More

White Matter Pathology in Dystonia

Neuroimaging and neuropathological changes in the genu of the internal capsule in spasmodic dysphonia. Read More

Brain Connections in Spasmodic Dysphonia

Diagram of disorganized functional connections between the sensorimotor brain regions involved in voice control during symptomatic and asymptomatic tasks in spasmodic dysphonia. Read More

The Simonyan Laboratory uses multi-modal neuroimaging approach to study central mechanisms of vocal motor control and to identify neuroimaging and neuropathological correlates of primary focal dystonias.

NEWS

Grape-Derived Compound Prevents Alzheimer's Disease Progression in Mice
May 2, 2012 - Mount Sinai researchers harnessed the beneficial effects of grape-seed extract on the brain and developed a biosynthetic compound that improves cognition in mice.

Researchers Gain Better Understanding of the Mechanism Behind Alzheimer's Disease Progression
May 1, 2012 - Mount Sinai scientists have determined how a pathological brain protein called tau contributes to the progression of Alzheimer's disease.

Decaffeinated Coffee Improves Brain Energy Metabolism in an Animal Study
February 2, 2012 - Mount Sinai researchers have found that decaffeinated coffee may reduce impaired brain energy metabolism associated with type 2 diabetes, a known risk factor for neurocognitive disorders.

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Kristina Simonyan, MD, PhD
Tel: 212-241-0656
Fax: 212-289-4107

Annenberg Building
1468 Madison Avenue
Department of Neurology
20th Floor, Room 20-84B
Box 1137
New York, NY 10029