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Shared Research Facilities (SRF)
Microvascular Surgery Shared Research Facility
Recanti/Miller Transplantation Institute
One Gustave L. Levy Place, Box 1504
New York, NY 10029
Director
Jonathan S. Bromberg, M.D., Ph.D.
Tel: (212) 659-8008
Fax: (212) 348-2474
E-mail: jon.bromberg@mountsinai.org
Manager
Peter Boros, M.D., Ph.D.
Tel: (212) 241-5589
E-mail: peter.boros@mssm.edu
The purpose of the Microvascular Surgery Shared Research Facility is to provide
microsurgical services for the Transplantation Institute and other research
laboratories within Mount Sinai. The facility has extensive experience in standard
microsurgical procedures as well as innovative techniques relevant to many
areas of biomedical research. For example, researchers on our staff developed
murine models of both orthotopic tracheal and small bowel transplantation.
The staff will teach basic and advanced microsurgical techniques to fellows,
surgical residents and medical students, as well as other research staff members
engaged in projects within Mount Sinai. We can also perform the procedures
listed below, or develop new ones if necessary, on a fee-for-service basis
that covers the costs of personnel and material.
The facility is staffed by two full-time microvascular surgeons who work under
the direction of Dr. Jonathan S. Bromberg and Dr. Peter Boros. The surgeons
are versatile in their abilities to perform a broad range of microsurgical
procedures in rodents. These procedures encompass a variety of complex transplant
and vascular procedures in rodent models, as well as other microsurgical procedures
important to medical research.
Below is a breakdown of the
procedures performed over the last three years:
Procedures Performed over the Last Three Years
| Procedure |
Rats |
Mice |
| Transplant |
| Liver (orthotopic) |
+ |
|
| Small Intestine (orthotopic) |
+ |
+ |
| Kidney |
+ |
+ |
| Pancreatic Islet |
+ |
+ |
| Heart (heterotopic) |
+ |
+ |
| Vascular |
+ |
+ |
| Trachea (orthotopic) |
|
+ |
| |
|
|
| General Techniques |
| Vector Administration |
+ |
+ |
| Catheter Placement |
+ |
+ |
| Skin Grafting |
+ |
+ |
| Vascular Intubation and Injection |
+ |
+ |
| |
|
|
| Other Surgical Procedures |
| Partial Hepatectomy |
+ |
+ |
| Bile Duct Ligation/Cannulation |
+ |
+ |
| Thymectomy |
+ |
+ |
| Splenectomy |
+ |
+ |
Services
Microvascular techniques and transplantation in
rodents.
Rats
- Orthotopic Liver Transplantation
- Orthotopic Small Intestine Transplantation
- Heterotopic Heart Transplantation
- Skin Grafting
- Pancreaticoduodenal Transplantation
- Pancreatic Islet Transplantation
- Vascular Transplantation
- Kidney Transplantation
- Catheter Placement
- Vascular Intubation and Injection
- Vector Administration
- Partial Hepatectomy, Bile duct Ligation/Cannulation
- Thymectomy, Splenectomy
Mice
- Heterotopic Vascularized and Nonvascularized
Heart Transplantation
- Heterotopic Small Intestine Transplantation
- Skin Grafting
- Pancreatic Islet Transplantation
- Pancreaticoduodenal Transplantation
- Vascular Transplantation
- Kidney Transplantation
- Catheter Placement
- Vascular Intubation and Injection
- Vector Administration
- Partial Hepatectomy, Bile duct Ligation/Cannulation
- Thymectomy, Splenectomy
Surgery is performed at two locations:
- East Bulding
Animal Facility
- Annenberg Building, 26th Floor
For additional or special procedures, contact the facility manager
or
director.
Shared Research Facilities
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