Shared Research Facilities (SRF)

Microvascular Surgery Shared Research Facility
Recanti/Miller Transplantation Institute

One Gustave L. Levy Place, Box 1504
New York, NY 10029

Director
Jonathan S. Bromberg, M.D., Ph.D.
Tel: (212) 659-8008
Fax: (212) 348-2474
E-mail: jon.bromberg@mountsinai.org

Manager
Peter Boros, M.D., Ph.D.
Tel: (212) 241-5589
E-mail: peter.boros@mssm.edu

The purpose of the Microvascular Surgery Shared Research Facility is to provide microsurgical services for the Transplantation Institute and other research laboratories within Mount Sinai. The facility has extensive experience in standard microsurgical procedures as well as innovative techniques relevant to many areas of biomedical research. For example, researchers on our staff developed murine models of both orthotopic tracheal and small bowel transplantation.

The staff will teach basic and advanced microsurgical techniques to fellows, surgical residents and medical students, as well as other research staff members engaged in projects within Mount Sinai. We can also perform the procedures listed below, or develop new ones if necessary, on a fee-for-service basis that covers the costs of personnel and material.

The facility is staffed by two full-time microvascular surgeons who work under the direction of Dr. Jonathan S. Bromberg and Dr. Peter Boros. The surgeons are versatile in their abilities to perform a broad range of microsurgical procedures in rodents. These procedures encompass a variety of complex transplant and vascular procedures in rodent models, as well as other microsurgical procedures important to medical research. Below is a breakdown of the procedures performed over the last three years:

Procedures Performed over the Last Three Years
Procedure Rats Mice
Transplant
Liver (orthotopic) +  
Small Intestine (orthotopic) + +
Kidney + +
Pancreatic Islet + +
Heart (heterotopic) + +
Vascular + +
Trachea (orthotopic)   +
     
General Techniques
Vector Administration + +
Catheter Placement + +
Skin Grafting + +
Vascular Intubation and Injection + +
     
Other Surgical Procedures
Partial Hepatectomy + +
Bile Duct Ligation/Cannulation + +
Thymectomy + +
Splenectomy + +
Total Number of Procedures by Type: 5/1/2000 - 12/31/2002

Services
Microvascular techniques and transplantation in rodents.

Rats

  • Orthotopic Liver Transplantation
  • Orthotopic Small Intestine Transplantation
  • Heterotopic Heart Transplantation
  • Skin Grafting
  • Pancreaticoduodenal Transplantation
  • Pancreatic Islet Transplantation
  • Vascular Transplantation
  • Kidney Transplantation
  • Catheter Placement
  • Vascular Intubation and Injection
  • Vector Administration
  • Partial Hepatectomy, Bile duct Ligation/Cannulation
  • Thymectomy, Splenectomy

Mice

  • Heterotopic Vascularized and Nonvascularized Heart Transplantation
  • Heterotopic Small Intestine Transplantation
  • Skin Grafting
  • Pancreatic Islet Transplantation
  • Pancreaticoduodenal Transplantation
  • Vascular Transplantation
  • Kidney Transplantation
  • Catheter Placement
  • Vascular Intubation and Injection
  • Vector Administration
  • Partial Hepatectomy, Bile duct Ligation/Cannulation
  • Thymectomy, Splenectomy

Surgery is performed at two locations:

  • East Bulding Animal Facility
  • Annenberg Building, 26th Floor

For additional or special procedures, contact the facility manager or director.


Shared Research Facilities