General Information

One of the main mandates of the Institutional Animal Care and Use Committee (IACUC) is to ensure that all vertebrate animal studies are conducted in accordance with Animal Welfare Act regulations and Public Health Service policies, and that such studies conform to the Institution's Assurance1 document filed with the Office of Laboratory Animal Welfare of the NI. To fulfill this requirement, all studies involving vertebrate animals, including pilot studies and intramural projects, must be reviewed and approved by the IACUC. Principal Investigators (PI's) are required to complete and submit an IACUC application entitled Vertebrate Animal Study. If the study involves biohazards, major surgery, genetically altered animals or production of antibodies, PI's are also required to complete additional appendices.

• Appendix A: Genetically Modified Animals is required for the production and/or use of genetically modified animals.
• Appendix B: Surgery is required if major surgery (survival or non-survival) is proposed, regardless of species.
• Appendix C: Antibody Production is required for the production of monoclonal or polyclonal antibodies.
• Biological Risk Assessment forms are required if the project involves the use of hazardous materials in-vivo.

Electronic Submission of IACUC Applications
IACUC forms and appendices are available on-line via the InfoEd portal.
For additional information, please contact the IACUC office at 212-241-0153.

IACUC Office Location
Annenberg Building, 26th Floor, Room 26-10, walk through security doors and make a right.

Full Committee Meetings
IACUC meetings are held every 3 weeks throughout the year.

Review Process
After reviewing the Vertebrate Animal Study and applicable appendices, the IACUC may approve, withhold approval, or require modifications of any proposed activities related to animal use and care. Once a study is approved, a formal letter of approval is sent by the IACUC to the investigator for use with extramural grant applications.

Studies can be initiated only after the application has been reviewed and has received a formal IACUC approval. Approvals are granted for a period of 3 years. For the second and third year of the approval period, only a progress report is required at the beginning of each project year. At the expiration of the 3-year approval period, a new set of IACUC forms must be submitted.

Contact Information
For additional information, contact the IACUC office at iacuc@mssm.edu.

Biological Risk Assessment
The Biological Risk Assessment forms are available on-line via the InfoEd portal.
For additional information, please contact the Biosafety Officer:
Philip Hauck, MS, MSHS, CBSP, SM (NRM)
Tel: 212-241-5169
Send e-mail

IACUC Office
Mount Sinai School of Medicine
One Gustave L. Levy Place
Box 1155
New York, NY 10029
Tel: 212-241-0153
Fax: 212-241-5550