In-Vivo Molecular Imaging Shared Research Facility

Overview Protocols Animal and Cell Imaging Personnel Pricing

Overview

The In-Vivo Molecular Imaging Laboratory (IMIL) is a MSSM shared resource facility serving the research community of Mount Sinai with equipment and imaging expertise. State-of-the-art bioluminescent as well as fluorescent imaging modalities are supported for in-vivo monitoring of cellular and genetic activity. Investigators are provided with cutting edge imaging technologies as well as analysis techniques. The long-term goal is to establish a comprehensive SRF for in-vivo molecular imaging using micro-MRI, micro-PET and other modalities.

IMIL is located behind the barrier in the animal facility of the Icahn Medical Institute allowing convenient access for investigators. The IMIL houses a Xenogen IVIS-200 Series imaging system with the integrated fluorescent imaging options. Simultaneous dual reporter in-vivo imaging is possible with bioluminescence and fluorescence probes. The imaging chamber has a gas anesthesia manifold that can accommodate up to 5 mice for simultaneously image acquisition. Selectable field of views allow in-plane (X,Y) imaging resolutions of up to 60-{micro}m. Integrated spectra filters allow for the determination of signal source depth (Z). For more detail on the system please read the specification of the instrument. pdf

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