Fang Laboratory

The Fang Laboratory’s research program involves biomechanics, development biology, and tissue engineering. A major focus is the mechanistic understanding of regulatory factors maintaining cell identity during musculoskeletal tissue development, mechanical adaptation, and pathogenesis.

Han Laboratory

The Han Laboratory develops cell-instructive biomaterials to study mechanisms of stem cell-niche interactions, disease modeling, stem cell manufacturing, and stem cell therapy, with the long-term goal of engineering therapies for treating skeletal muscle trauma and diseases.

Holguin Laboratory

The Holguin Laboratory studies the biomechanics and mechanobiology of the spine as it adapts to aging, mechanical forces, genetics, and injury. Molecular, histologic, imaging, biomechanical, and genetic rodent model techniques are utilized, all with an eye toward potential therapies.

Hubmacher Laboratory

The research at the Hubmacher Laboratory focuses on the role of the extracellular matrix, or the “glue” that holds the cells together, in the formation and function of musculoskeletal tissues. Knowledge of these mechanisms may contribute toward the identification of novel tissue engineering approaches.

Iatridis Laboratory

As a member of both the Orthopedic Research Laboratories and the Black Family Stem Cell Institute, the objective of the Iatridis Spine Bioengineering Lab is to develop minimally invasive interventions to prevent and repair painful spinal pathologies, with specific focus on intervertebral disc degeneration. 

Cho Spine Laboratory

The Samuel Cho Spine Laboratory conducts scientific analysis of radiographic, perioperative, and clinical data to develop algorithms and methods that influence surgical strategies and patient-centered treatments toward optimal outcomes.

Hausman/Cagle Upper Extremity and Nerve Laboratory

The Hausman/Cagle Upper Extremity and Nerve Laboratory is dedicated to improving the outcomes of peripheral nerve injuries by developing novel imaging modalities and assessments of peripheral nerve damage and function. The team also focuses on clinical and experimental biomechanics to improve surgical outcomes of patients with hand, wrist, elbow, and shoulder injuries.