Our research at the Mindich Child Health and Development Institute (MCHDI) is multidisciplinary, emphasizing the role of genetics and genomics in understanding the pathogenesis of diseases of infants, children, and adolescents and on developing novel therapeutic approaches. Our goal is to maximize the use of genetic information to improve the lives of children through the development of new therapies, the tailoring of existing drugs to maximize efficacy while minimizing adverse effects, and rationalizing population-level interventions related to environmental exposures.
We enable existing departments, institutes, and clinical research programs at the Icahn School of Medicine at Mount Sinai (ISMMS) to leverage resources and accelerate achievements, working with many departments and institutes across the Mount Sinai Health System.
Areas of Research Emphasis
We are dedicated to conducting and facilitating translational research with an emphasis on genomic and environmental studies to better understand the pathogenesis of prevalent pediatric conditions and diseases. In addition, we are interested in exploring prevalent pediatric diseases that exhibit complex genetic patterns, such as neurodevelopmental disorders and certain birth defects, as well as the interface between children’s genetic makeup and their environment, especially as it correlates to conditions such as asthma/allergy, obesity, and developmental outcomes.